Efficacy and Safety of Entecavir Plus Carnitine Complex (GODEX) Compared to Entecavir Monotherapy in Patient with Alt Elevated Chronic Hepatitis B: Randomized, Multicenter Open Label Trials. The Goal Study

Carnitine and vitamin complex (Godex®) is widely used in patients with chronic liver disease who show elevated liver enzyme in South Korea. The purpose of this study is to identify the efficacy and safety of carnitine from entecavir combination therapy in Alanine aminotransferase (ALT) elevated Chronic Hepatitis B (CHB) patients.

L-Carnitine Supplementation to Diet: A New Tool in Treatment of Non-alcoholic Steatohepatitis – A Randomized and Controlled Clinical Trial

Non-alcoholic steatohepatitis (NASH) is a known metabolic disorder of the liver. No treatment has been conclusively shown to improve NASH or prevent disease progression. The function of L-carnitine to modulate lipid profile, glucose metabolism, oxidative stress, and inflammatory responses has been shown. The aim of this study was to evaluate the effects of L-carnitine’s supplementation on regression of NASH.

Effects of Carnitine Orotate on Peripheral Blood Mitochondrial DNA Copy Number and Liver Function in Non-alcoholic Fatty Liver Disease

Functional and anatomical abnormalities of mitochondria play an important role in developing steatohepatitis. Carnitine is essential for enhanced mitochondrial beta oxidation through the transfer of long-chain fatty acids into the mitochondria. We examined the impact of carnitine orotate (GODEX) on liver function and peripheral blood mitochondria copy number in NAFLD patients.